Boosting energy at cell-level and help restore and maintain a healthy body

alphaH® removes oxidative stress and associated diseases.

alphaH® enhances oxygen utilization and the muscle protein synthesis, making it a relevant dietary supplement during a rehabilitation period, in connection with hospitalization, operations, illness or in connection with sports performances.

alphaH® is a new dietary supplement by HG Pharma.

Besides being closely related to aging processes, oxidative stress is complicit in a high percentage of all diseases (Atherosclerosis, diabetes, neurodegenerative diseases, rheumatoid arthritis, and cancer). Oxidative stress is described as an imbalance of oxidative and antioxidative processes that are triggered by free radicals in the body’s cellular metabolic processes. 
The active substances and ingredients of alphaH® provide a reduction of oxidative stress due to a preventive and concomitant reduction of metabolic changes in the body at cellular level. This makes alphaH® particularly suitable for use in posttraumatic syndrome, in the perioperative phase and for regeneration after interventions and in metabolic dysregulation.
alphaH℗ counteract the body’s stress responses to physical trauma caused by exercise, by improving physical well being and performance and reducing oxidative stress.

alphaH ein Nahrungsergänzungsmittel

The active substances and ingredients of alphaH® are proven to provide an improvement in physical performance and reduction of oxidative stress*

 Oxidative stress and diseases

Oxidative stress is essentially an imbalance between the production of free radicals and the ability of the body to counteract or detoxify their harmful effects through neutralization by antioxidants. It is a known byproduct of Free Radical damage to the cellular structures in our bodies.
The results of many peer-reviewed studies have shown oxidative stress caused by Free Radicals to be one of the primary instigators of hundreds of diseases and ailment, including aging.

  • Improves general condition and physical performance combined with faster recovery and rehabilitation (1, 2, 3)
  • Prevents and disrupts the harmful changes in the body caused by oxidative stress reactions (1, 4)
  • Strengthens oxygen utilization and muscle-protein synthesis in rehabilitation(1, 5, 6, 8, 9, 10)

*) 1, 5, 6, 8, 9, 10

alphaH® causes a preventive and concomitant reduction of metabolic changes. These changes are stress responses to physical trauma caused by exercise. alphaH® counteracts this by improving physical performance and reducing oxidative stress.

Rheuma diseases

alphaH® is able to reduce inflammation damage and reduces, therefore, the damage of chronic inflammation and source of pain

Fertility in Men 

alphaH® is able to reduce free radical species (ROS), who are responsible for reduced sperm count and decreased motley of sperms

Post Trauma & Hospitalization

alphaH® is an effective supplement to reduce post-traumatic syndrome and enhances recovery, resulting in a reduction of hospitalization time.

Before surgery, especially in poor health

alphaH® is used for perioperative (pre-and post-operative) surgery optimization. Applications range from tumor surgery, vascular surgery, cardiac surgery, thoracic surgery, and plastic surgery, to well as general surgery, trauma surgery, and orthopedics.biologic therapy shows a reduction of oxidative stress and improvement of the Vitamin D status and Vitamin D transport system.

Rehabilitation patients

alphaH ® is used for postoperative care, as well as after accidents and serious illnesses to optimize and increase the speed of the healing process.

Sports performances 

alphaH® is a natural regenerative and performance-enhancing drink combating oxidative stress in the body. Scientific research shows that it boosts health at cell-level and help maintain a healthy body. In everyday use, AlphaH® delivers a greater resistance to Stress, Fatigue, Injury, and illness. It enhances the ability to perform and to concentrate.
The active compounds in alphaH® have been successfully adopted by world-class athletes due to its scientifically evaluated proven benefits and WADA approval.

Lifestyle Stress – Performance and Cleansing

  • The intake of alphaH® causes an energy recovery (ATP) in the cells
  • an optimization of oxygen utilisation a high antioxidant potential
  • a buildup of nonessential amino acids
  • a degradation of toxic substances

The active ingredients of alphaH® work synergistically

The active substances of alphaH® are:

AKG (alpha-ketoglutaric acid)

5HMF (5Hydroxymethyl-Furfural)

Carnosine (beta-alanyl-L-histidine)

From numerous observational studies and studies it can be summarized that the ingredients of alphaH® work synergistically.

For example, while vitamin C /alpha-ketoglutaric acid (AKG) degrades Peroxides after a short time, Vitamin C / 5-hydroxymethylfurfural (5-HMF) prevents the modification, oxidation/nitration of proteins.

The energy production in the cells via ATP is supported by high vitamin C / AKG concentrations in human tissue by 5HMF, with a simultaneous optimization of oxygen utilization.

The high antioxidant potential of AKG in the elimination of free oxygen radicals, combined with the potential of 5HMF in the neutralization of RONS, results in an effective interaction of the active ingredients in the antioxidant network of the organism and can u.a. also a “recycling” of vitamin C (de-radicalisation) with it.

By building non-essential amino acids (e.g., glutamine) and breaking down toxic substances in the form of urea by AlphaH℗ an efficient intervention in the treatment of Oxidative stress occurs.

Active ingredient AKG (alpha-ketoglutaric acid)

The AKG is a natural nitrogen-free part of the amino acids found in body cells, from which glutamine and glutamic acid is formed. It is a key biological intermediate of ATP production for energy production in the cell (Citrate or citric acid cycle)
The AKG’s action is enhanced by its strong reactivity, making it a stronger radical scavenger (RONS) than vitamin C. In addition, she does not participate in the degradation of free radicals necessary for immune defense. The AKG also has an important function in the oxidation reactions with molecular oxygen (e.g., AKDHG) to prevent tissue damage or Dysfunctions (O2 sensor).
As a nitrogen regulator in the metabolism, it prevents nitrogen overload (NH4 +) by reacting to glutamine.
The resulting stimulating neurotransmitter glutamate leads to the enzymatically controlled detoxification of ammonia from the tissue (e.g., in liver damage, in the central nervous system).

Active ingredient Carnosine (beta-alanyl-L-histidine)

Carnosine (-alanyl-L-histidine) was discovered in 1900 as an abundant non-protein nitrogen-containing compound of meat. The dipeptide is not only found in skeletal muscle, but also in other excitable tissues. The physiological roles of carnosine is based on its biochemical properties. The latter include pH-buffering, metal-ion chelation, and antioxidant capacity as well as the capacity to protect against the formation of advanced glycation and lipoxidation end-products. For these reasons, the therapeutic potential of carnosine supplementation has been tested in numerous dis- eases in which ischemic or oxidative stress is involved. For several pathologies, such as diabetes and its complications, ocular disease, aging, and neurological disorders, promising preclinical and clinical results have been obtained. (to read more)

Active substance 5HMF (5Hydroxymethyl-Furfural)

5HMF is a natural active ingredient that is formed as a non-enzymatic browning reaction in the thermal decomposition of sugars and carbohydrates (Maillard reaction). It is contained in natural form in honey, apple juice, citrus fruits, beer etc.
Similar to AKG, 5HMF is a radical scavenger (O2, OH) and has a stronger effect on vitamin C than reactive nitrogen radicals (RNS).  5HMF is able to bind to an increased extent, in an enzyme-independent reaction, ammonia and free amines (non-enzymatic detoxification, similar to urea cycle).
It reacts with reactive nitrogen compounds (RNA) like peroxynitrite and binds free radicals. Due to its antioxidant capacity, 5HMF protects the molecular oxygen in the body against radicalization and thus leads to a better utilization of oxygen. 5HMF also prevents iron (II) and hydrogen peroxide (= Fentional reaction) induced cell damage.
It strengthens the antioxidant network in the body through the increased formation of antioxidant-regulating enzymes (SOD, GPx) and reacts with ONOO- by forming a metastable substance. In addition, via the property of binding amines via the azomethine reaction, the antioxidant effect is enhanced.

alphaH® is a natural remedy and dietary supplement, that is ordinated and administered by Doctors.
Recommended intake:

  • Pre-operatively: 2 x 20 mL of alphaH® for 10 days before surgery / intervention.
  • Post-operatively: 1 x 20 mL of alphaH® for 10 after surgery / intervention.
  • Rehabilitation and Sports: 1 x 20 mL of alphaH® a day during the rehabilitation phase

The intake of alphaH® causes:

  • an energy recovery (ATP) in the cells
  • an optimization of oxygen utilization
  • a high antioxidant potential
  • a buildup of nonessential amino acids
  • a degradation of toxic substances

The ingredients used in alphaH® are:

  • of purely natural origin
  • without glucose
  • without fructose
  • without lactose
  • protected by patents
  • proven by clinically reproducible results

Scientific documentation and references

  1. M. Gatt, J. Macfie, Br J Surg 92, 494 (2005).
  2. K. Holte, H. Kehlet, J Am Coll Surg 202, 971 (2006).
  3. M. Kremer, A. Ulrich, M. W. Büchler, W. Uhl, Recent Results Cancer Res 165, 14 (2005).
  4. P. Mattei, J. L. Rombeau, World J Surg 30, 1382 (2006).
  5. J. Nygren et al., Clin Nutr 24, 455 (2005).
  6. G. A. van Mastrigt, J. G. Maessen, J. Heijmans, J. L. Severens, M. H. Prins, Crit Care Med 34, 1624 (2006).
  7. C. J. Walter, A. Smith, P. Guillou, Ann R Coll Surg Engl 88, 191 (2006).
  8. L. C. Azevedo, M. Janiszewski, F. G. Soriano, F. R. Laurindo, Endocr Metab Immune Disord Drug Targets 6, 159 (2006).
  9. E. M. Bulger, R. V. Maier, Arch Surg 136, 1201 (2001).
  10. E. Crimi et al., Free Radic Biol Med 40, 398 (2006).
  11. J. Macdonald, H. F. Galley, N. R. Webster, Br J Anaesth 90, 221 (2003).
  12. A. B. Nathens et al., Ann Surg 236, 814 (2002).
  13. K. M. Oldham, P. E. Bowen, J Am Diet Assoc 98, 1001 (1998).
  14. S. Sakaguchi, S. Furusawa, FEMS Immunol Med Microbiol 47, 167 (2006).
  15. R. K. Thimmulappa et al., J Clin Invest 116, 984 (2006).
  16. M. Valko, C. J. Rhodes, J. Moncol, M. Izakovic, M. Mazur, Chem Biol Interact 160, 1 (2006).
  17. V. M. Victor, M. Rocha, M. De la Fuente, Int Immunopharmacol 4, 327 (2004).
  18. V. M. Victor, M. Rocha, J. V. Esplugues, M. De la Fuente, Curr Pharm Des 11, 3141 (2005).
  19. F. Bozzetti, Nutrition 18, 953 (2002).
  20. M. Braga, L. Gianotti, JPEN J Parenter Enteral Nutr 29, S57 (2005).
  21. H. Kehlet, Br J Anaesth 78, 606 (1997).
  22. J. Rosenberg, H. Kehlet, Ugeskr Laeger 163, 908 (2001).
  23. D. H. Harpole et al., Ann Thorac Surg 61, 977 (1996).
  24. R. L. Doyle, Chest 115, 77S (1999).

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